A rare inflammatory disease associated with COVID-19 that affects young children. The majority of patients have tested negative for the novel coronavirus but positive for antibodies, indicating they had previously had COVID-19 but don't have a current infection. Some of the children have presented with some or all of the features associated with Kawasaki disease, an illness seen in children that can result in enlargement or aneurysms of the coronary arteries among other indicators. Symptoms have included fever, rash, conjunctivitis, red swollen hands and red, cracked lips. Some children had clinical and laboratory signs of an exaggerated systemic immune response that has caused organ damage in adults with COVID-19. Many children had coagulopathies, a condition in which the blood's ability to coagulate is impaired; cardiac dysfunction; diarrhea, abdominal distension, vomiting and other GI symptoms; or acute kidney injury. To date, most children affected have done well. Treatments have included anticoagulation, IV immunoglobulin, IL-1 or IL-6 blockade and corticosteroids. Some children have only needed supportive care.
No programs.